Epigenetic Age Acceleration and Its Link to Healthy Longevity in Older Women

By Max Cerquetti % B% d,% Y | Alzheimer's Alzheimer’s disease antienvejecimiento biological clocks Cellular Senescence chronological age cognition cognitive function Cognitive Health DNA methylation eAge epigenetic age epigenetic alterations Epigenetic Clock epigenetische Alter Epigenetische Uhr gene expression Genexpression genomic instability genomics hallmarks of aging healthy aging salud cardíaca Horvath clock Human longevity Kognitive Gesundheit live longer mental health salud metabólica Zelluläre Seneszenz

IntroductionAs the world's population ages, understanding the factors that contribute to healthy aging becomes increasingly important. One area of research that has garnered attention is the study of epigenetic age acceleration (EAA). EAA refers to the difference between a person's biological age, as measured by specific changes in their DNA,...

Los relojes epigenéticos como predictores de la edad: su historia, fortalezas y limitaciones

By Max Cerquetti % B% d,% Y | chAge chronological age DNA methylation DNAm eAge epigenetic age Epigenetic Clock Horvath clock

Sabemos muy bien que la vejez es el principal factor de riesgo de cáncer, enfermedades cardiovasculares y neurodegeneración. De manera frustrante, los avances en la investigación sobre el envejecimiento se retrasaron durante muchos años debido a la escasa fiabilidad de las herramientas utilizadas para predecir la tasa de envejecimiento biológico...